Nature Biotechnology, Published online: 11 May 2026; doi:10.1038/s41587-026-03155-8 While circRNA is often framed as a more stable, longer-lasting alternative to linear mRNA, its real-world advantages remain largely theoretical, and it is unclear whether greater molecular stability will translate into meaningful clinical gains.。
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Circling back to RNA vaccines
Nature Biotechnology, Published online: 11 May 2026; doi:10.1038/s41587-026-03155-8 While circRNA is often framed as a more stable, longer-lasting alternative to linear mRNA, its real-world advantages remain largely theoretical, and it is unclear whether greater molecular stability will translate into meaningful clinical gains.。